Post by pepo on Jul 27, 2014 12:07:34 GMT -4
Postdoctoral positions are available immediately to work in the area of hypoxia, nutrient signaling and stem cell biology in the context of human disease
POSTDOCTORAL POSITION, MD ANDERSON CANCER CENTER
Cullen Taniguchi, MD PhD
Postdoctoral positions are immediately available in laboratory of Dr. Cullen Taniguchi in the Department of Experimental Radiation Oncology at The University of Texas MD Anderson Cancer Center. The laboratory is devoted to understanding the role of hypoxic and metabolic signaling in the initiation and progression of cancer, diabetes and other human disorders. We are particularly interested in dissecting the contribution of hypoxic and metabolic signaling in the tumor microenvironment. The contribution of local stem cell niches and/or paracrine signaling to tumor progression and treatment efficacy will also be explored. We have already developed mouse models to activate hypoxia and growth factor signaling in specific tissues and niches in order to study the role of these pathways on cancer progression and metabolic disorders. This multidisciplinary lab will afford significant creative and intellectual freedom to a highly motivated candidate.
We are seeking individuals with an expected or recently earned M.D. or Ph.D. who have significant experience and knowledge in molecular biology, cell biology and/or mouse models of disease. Our lab will utilize novel techniques to modulate pathways of interest with complete spatiotemporal control in animals and in cells. In vivo experiments will be complemented with in vitro screens based on CRISPR, shRNA, or small molecule libraries. Transcriptome profiling by RNA seq or microarrays will also be used. There will be ample opportunities to translate the basic research progress in the lab to the vast clinical infrastructure at MD Anderson, should the candidate wish to explore these avenues of inquiry. All levels of experience will be considered, and pay will be commensurate with experience.
Knowledge and expertise with mouse modeling, next generation sequencing and library screens is highly desirable but not required. Experience in the field of hypoxia, growth factor signaling, and metabolism is desirable but not critical as training and teaching is readily available. Experience in database organization, designing and performing complex experiments, and excellent communication skills are essential.
References:
Nature Medicine, 2013 19(10): 1325-1330
Sci Transl Med. 2014 May 14;6(236):236ra64
J Clin Invest. 2005 Mar;115(3):718-27.
MD Anderson Cancer Center is ranked No. 1 in cancer care in the United States by the U.S. News and World Report’s “America’s Best Hospitals” survey. It ranks first in the number of awarded grants from National Cancer Institute. It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest biomedical center.
The interested candidates should send a CV, 2-3 letters of reference (if available) and a research statement describing their research interests and career goals to Dr. Cullen Taniguchi at taniguch@stanford.edu
POSTDOCTORAL POSITION, MD ANDERSON CANCER CENTER
Cullen Taniguchi, MD PhD
Postdoctoral positions are immediately available in laboratory of Dr. Cullen Taniguchi in the Department of Experimental Radiation Oncology at The University of Texas MD Anderson Cancer Center. The laboratory is devoted to understanding the role of hypoxic and metabolic signaling in the initiation and progression of cancer, diabetes and other human disorders. We are particularly interested in dissecting the contribution of hypoxic and metabolic signaling in the tumor microenvironment. The contribution of local stem cell niches and/or paracrine signaling to tumor progression and treatment efficacy will also be explored. We have already developed mouse models to activate hypoxia and growth factor signaling in specific tissues and niches in order to study the role of these pathways on cancer progression and metabolic disorders. This multidisciplinary lab will afford significant creative and intellectual freedom to a highly motivated candidate.
We are seeking individuals with an expected or recently earned M.D. or Ph.D. who have significant experience and knowledge in molecular biology, cell biology and/or mouse models of disease. Our lab will utilize novel techniques to modulate pathways of interest with complete spatiotemporal control in animals and in cells. In vivo experiments will be complemented with in vitro screens based on CRISPR, shRNA, or small molecule libraries. Transcriptome profiling by RNA seq or microarrays will also be used. There will be ample opportunities to translate the basic research progress in the lab to the vast clinical infrastructure at MD Anderson, should the candidate wish to explore these avenues of inquiry. All levels of experience will be considered, and pay will be commensurate with experience.
Knowledge and expertise with mouse modeling, next generation sequencing and library screens is highly desirable but not required. Experience in the field of hypoxia, growth factor signaling, and metabolism is desirable but not critical as training and teaching is readily available. Experience in database organization, designing and performing complex experiments, and excellent communication skills are essential.
References:
Nature Medicine, 2013 19(10): 1325-1330
Sci Transl Med. 2014 May 14;6(236):236ra64
J Clin Invest. 2005 Mar;115(3):718-27.
MD Anderson Cancer Center is ranked No. 1 in cancer care in the United States by the U.S. News and World Report’s “America’s Best Hospitals” survey. It ranks first in the number of awarded grants from National Cancer Institute. It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest biomedical center.
The interested candidates should send a CV, 2-3 letters of reference (if available) and a research statement describing their research interests and career goals to Dr. Cullen Taniguchi at taniguch@stanford.edu